22)  ANSWER

B) Severe facial acne

Explanation

Oral contraceptives can reduce acne; result in signs and symptoms of early pregnancy, including chloasma; and accelerate the progress of gallbladder disease. Birth control pills do not provide protection against STIs that can result in PID. This question is actually asking about secondary uses of oral contraceptives. Eliminate option 1 first because it is the least plausible. Eliminate options 3 and 4 next because they are aggravated by the use of oral contraceptives.